Veterans Special Report

Clinical Trial – The Effect of Hyperbaric Oxygen Therapy on Patients Suffering From Neurologic Deficiency Due Traumatic Brain Injury

by | Jul 14, 2008 | Clinical Trials, HBOT Research, Neurologic Deficiency

Traumatic brain injuries (TBI) are a major cause of morbidity and mortality worldwide. Due to
improvements in emergency medical care, transportation and specialized trauma facilities, the
number of people surviving TBI with impairment has significantly increased in recent years.
The long term cognitive sequelae, which are often not visible persist far beyond the
resolution of the obvious physical disabilities. This combined with the relatively low
awareness of the general public has designated TBI as the "silent epidemic" (TBI CDC 2006).
Hyperbaric oxygen therapy (HBOT) has been suggested as a possible treatment modality for
these cases and preliminary studies are promising.

The purpose of this study is to evaluate the effectiveness of HBOT in the treatment of
chronic mild traumatic brain injuries (mTBI). Sequential SPECT scans of the brain and
neurocognitive testing will be used to evaluate cerebral blood flow (CBF) response, cognitive
and functional improvement following treatment.

Liposome encapsulation reduces cantharidin toxicity.

by | Jan 10, 2008 | Cancer

Abstract: Several reports have demonstrated that cantharidin is a strong anticancer compound in vitro; however, its in vivo usefulness is often limited due to its high systemic toxicity. In this study, we encapsulated cantharidin into pegylated liposomes and studied...

Hypoxic radiosensitization: adored and ignored.

by | Sep 11, 2007 | Cancer

Abstract: Since observations from the beginning of the last century, it has become well established that solid tumors may contain oxygen-deficient hypoxic areas and that cells in such areas may cause tumors to become radioresistant. Identifying hypoxic cells in human...