by HBOT News | Aug 3, 2017 | Post-Traumatic Stress Disorder (PTSD)
We report results of an observational cohort study investigating long-term follow-up in participants from two completed United States military trials of hyperbaric oxygen (HBO₂) for persistent post-concussive symptoms (PCS), as well as challenges in recruitment and retention in active-duty military personnel. After informed consent, participants completed an electronic survey assessing PCS, post-traumatic stress disorder (PTSD), anxiety, depression and quality of life. Of 132 HBO₂ study participants, 40 (30%) completed the survey (42 could not be contacted; 50 were lost to follow-up or declined). All were male, age 28.1 ±6.6 years (mean ±1SD). Time to follow-up was 39.2 ±6.1 months.
by HBOT News | Aug 3, 2017 | Concussion, Traumatic Brain Injury (TBI)
Baseline sleep characteristics were explored for 71 U.S. military service members with mild traumatic brain injury (mTBI) enrolled in a post-concussive syndrome clinical trial. The Pittsburgh Sleep Quality Index (PSQI), sleep diary, several disorder-specific questionnaires, actigraphy and polysomnographic nap were collected. Almost all (97%) reported ongoing sleep problems. The mean global PSQI score was 13.5 (SD=3.8) and 87% met insomnia criteria. Sleep maintenance efficiency was 79.1% for PSQI, 82.7% for sleep diary and 90.5% for actigraphy; total sleep time was 288, 302 and 400 minutes, respectively. There was no correlation between actigraphy and subjective questionnaires. Overall, 70% met hypersomnia conditions, 70% were at high risk for obstructive sleep apnea (OSA), 32% were symptomatic for restless legs syndrome, and 6% reported cataplexy. Nearly half (44%) reported coexisting insomnia, hypersomnia and high OSA risk. Participants with post-traumatic stress disorder (PTSD) had higher PSQI scores and increased OSA risk. Older participants and those with higher aggression, anxiety or depression also had increased OSA risk. The results confirm poor sleep quality in mTBI with insomnia, hypersomnia, and OSA risk higher than previously reported, and imply sleep disorders in mTBI may be underdiagnosed or exacerbated by comorbid PTSD.
by HBOT News | Jul 15, 2017 | Key TBI Research, TBI (Traumatic Brain Injury), Traumatic Brain Injury (TBI) News
Abstract Studies of the association between traumatic brain injury (TBI) and suicide attempt have yielded conflicting results. Furthermore, no studies have examined the possible mediating role of common comorbid psychiatric conditions in this association. This study...
by HBOT News | May 2, 2017 | Chronic Interstitial Cystitis, Clinical Trials, HBOT Research
Pilot study to determine feasibility for treating patients with two chronic inflammatory
conditions of the urinary bladder: chronic interstitial cystitis and recurrent urinary tract
infections using a standardized hyperbaric oxygen treatment plan. Presently there are no good
treatments for these conditions and hyperbaric oxygen may be a safe and readily accessible
therapy as it has proven successful an another type of chronic inflammatory condition of the
urinary bladder known as "radiation cystitis". The study will determine if patients will
consider this an acceptable treatment for their conditions and that it is well tolerated.
by HBOT News | Nov 8, 2016 | Cancer
Abstract: To assess the risk of mood disorders among patients with colorectal cancer (CRC), a population-based cohort study was performed using the Taiwanese National Health Insurance Research Database. The study cohort included 27242 patients diagnosed with CRC...
