Immersion pulmonary edema and comorbidities: case series and updated review.
Abstract: Immersion pulmonary edema (IPE) occurs in swimmers (especially triathletes) and scuba divers. Its pathophysiology and risk factors are incompletely understood. This study was designed to establish the prevalence of preexisting comorbidities in individuals...Clinical Trial – The Using of NEurocryostimulation in Military Ankle Sprains
Introduction: The military population is at high-risk for injury with by painful sprains,
especially of the ankle. The referenced treatment method for pain is the cryotherapy,
consisting in applying cold-packs to the injured ankle several times a day. However, another
pain treatment has been developed and is commonly used by high-level sports teams and
rheumatologists but its efficacy has never been assessed within a military population, i.e.
the hyperbaric CO2 cryotherapy, also called the neurocryostimulation.
Research design: This study was carried out on a French multicenter basis, the study
consisting in a randomized controlled superiority trial and open-label prospective analysis
in the treatment of 40-year-old military patients or younger suffering from acute ankle
sprains. Two groups were made: patients were treated either by neurocryostimulation or by the
referenced cryotherapy (cold-packs). The care protocol for both groups consisted in six
supervised 30 minute-sessions within a period of three consecutive days.
Hypothesis: Neurocryostimulation is more effective in the treatment of pain severity
resulting from an ankle sprain than the referenced treatment by cold-packs. Moreover, we
theorized that the total consumption of paracetamol and the number of days of temporary
inaptitude and of work exemption were lower in patients treated by neurocryostimulation.
Outcomes:
For each session, pain severity is assessed on a 100-mm Visual Analog Scale at the beginning
and at the end of session 20 minutes later after a four-step walk.