Clinical Trial – Hyperbaric Oxygen Therapy in Patients With Chronic Stable Ischemic Heart Disease: An Option for Therapeutic Angiogenesis?

Hyperbaric oxygen therapy (HBOT) is proposed as a possible in vivo angiogenic stimulator for
improving microvascular myocardial perfusion and anginal symptoms as assessed by myocardial
perfusion imaging and angina questionnaire in patients with chronic stable ischemic heart
disease, when no other means to relief symptoms and/or ischemia are available.

Clinical Trial – Comparison of Two Regional Technics In Knee Artroplasty

Purpose: This prospective, randomised, controlled, single-blind, multicentre study was
designed to investigate the effects of peripheral nerve block methods (applied using
unilateral spinal anaesthesia [USA] on elderly patients scheduled to undergo total knee
arthroplasty) on perioperative haemodynamic parameters and the postoperative analgesia
period.

Materials and Methods: Sixty patients in the American Society of Anesthesiologists (ASA)
Physical Status II-III group were randomly divided into two groups. Spinal anaesthesia was
performed in the USA group, in the lateral position through the intervertebral space, with 2
ml of hyperbaric bupivacaine (L4-L5 or L3-L4); 0.5% bupivacaine hydrochloride and 2%
lidocaine were combined for the psoas compartment-sciatic (PCS) group, and the mixture was
used for psoas compartment block (PCB) and sciatic nerve block. The haemodynamic parameters
were recorded every 5 minutes until the end of the preoperative and perioperative operation
periods and postoperative first analgesic application time.