by HBOT News | May 7, 2015 | Chronic Heart Failure
Abstract: Since 2009, the United Kingdom diving incident data show an increasing number of fatalities in the over-50s age group. Previous studies also suggest some divers take cardiac medications. Since 2001, diving medicals have not been mandatory for UK sport...
by HBOT News | May 1, 2015 | Key Crohn's Disease Research, Key Inflammatory Bowel Disease (IBD) Research, Key Ulcerative Colitis Research
Recent studies have suggested that nitric oxide (NO.), the product of nitric oxide synthase in inflammatory cells, may play a part in tissue injury and inflammation through its oxidative metabolism. In this study the colonic generation of oxides of nitrogen (NOx) and nitric oxide synthase activity was determined in ulcerative colitis and Crohn’s disease. Colonic biopsy specimens were obtained from inflammatory bowel disease patients and from normal controls. Mucosal explants were cultured in vitro for 24 hours and NOx generation was determined. Nitric oxide synthase activity was monitored by the conversion of [3H]-L-arginine to citrulline. Median NOx generation by inflamed colonic mucosa of patients with active ulcerative colitis and Crohn’s colitis was 4.2- and 8.1-fold respectively higher than that by normal human colonic mucosa. In ulcerative colitis and Crohn’s colitis nitric oxide synthase activity was 10.0- and 3.8-fold respectively higher than in normal subjects.
by HBOT News | Apr 29, 2015 | Chronic Wounds
Abstract: Several studies have shown a pathological oxygenation (hypoxia/hyperoxia) on the adipose tissue in obese subjects. Additionally, the excess of body weight is often accompanied by a state of chronic low-degree inflammation. The inflammation phenomenon is a...
by HBOT News | Apr 24, 2015 | Necrotizing Fasciitis
Abstract: Pyoderma gangrenosum (PG) is associated with systemic disease, mostly rheumatoid arthritis (RA) and inflammatory bowel disease (IBD), in many patients (more than 50%). Lesions associated with arthritis are often ulcerative. Although these lesions...
by HBOT News | Apr 24, 2015 | Chronic Wounds
Abstract: Cadexomer iodine (CI) was evaluated as a palliative wound care dressing for foot ulcers in chronic critical limb ischemia (CCLI) given its ability to prevent infection and absorb moisture. A retrospective study of 11 patients with CCLI and wounds on distal...