Clinical Trial – Thermal Radiofrequency Versus Neurolytic Saddle Rhizotomyfor Severe Pereneal Cancer Pain
The control of perineal malignant pain is difficult and challenging for pain physicians.
Different modalities have been tried to treat this complex pain syndrome including
pharmacotherapy and interventional therapy.
Neuroaxial phenol rhizolysis is simple and cheap option. However; for patients with pelvic or
rectal neoplasms and intact bowel and bladder sphincteric functions, there are neurosurgical
recomendations of selective sacral nerve roots rhizotomy blockade "as an alternative to
chemical saddle rhizotomy".
Hyperbaric oxygen attenuates neuropathic pain and reverses inflammatory signaling likely via the Kindlin-1/Wnt-10a signaling pathway in the chronic pain injury model in rats.
Abstract: Hyperbaric oxygen (HBO) therapy is proven to attenuate neuropathic pain in rodents. The goal of the present study was to determine the potential involvement of the Kindlin-1/Wnt-10a signaling pathway during astrocyte activation and inflammation in a rodent...Hyperbaric oxygen attenuates neuropathic pain and reverses inflammatory signaling likely via the Kindlin-1/Wnt-10a signaling pathway in the chronic pain injury model in rats.
Abstract: Hyperbaric oxygen (HBO) therapy is proven to attenuate neuropathic pain in rodents. The goal of the present study was to determine the potential involvement of the Kindlin-1/Wnt-10a signaling pathway during astrocyte activation and inflammation in a rodent...Clinical Trial – intrathecaم Ketamine, Morphine and Both for Lower Abdominal Cancer Surgery Pain
this study investigates the analgesic efficacy and other possible effects of ketamine,
morphine, and both together when administered intrathecally for control of postoperative pain
following lower abdominal cancer surgeries.