Recent studies have shown that hyperbaric oxygen therapy (HBOT) can induce angiogenesis and
improve impaired organ function. HBOT was also recently suggested as a possible therapy for
ED due to surgical injuries. However, the effect of HBOT on non-surgical related ED has not
been investigated to date.
The objective in this study was to assess the effect of HBOT on patients with ED by means of
sexual function questionnaires and novel imaging techniques.
Dexamethasone, a high-potency, long-acting glucocorticoid, when added to bupivacaine, it
extended the duration of analgesia. We aim to study the effectiveness of spinal dexamethasone
in Transuretheral prostatectomy.
Placental insufficiency is responsible for fetal loss in about 40% of all stillbirths and
long term neurological deficits. The mean interval from diagnosis of brain sparing of severe
IUGR fetuses to delivery has been recently identified by only seven days (Flood K et al, Am J
Obstetrics and Gynecology 2014).
The critical placental player in the active amino acids (AA) transport from the mother to the
fetus is the trophoblast, which is irreversibly changed in severe IUGR fetuses caused by
placental insufficiency. Thus, a logical partial solution of IUGR could be the direct supply
of AAs and glucose to the fetus, in order to improve the fetal growth, normalize the fetal
programming and to prolong the pregnancy.
The aim of this prospective pilot study is to further test the efficacy of the administration
of AAs and glucose supplementation with hyperbaric oxygenation (HBO), via a subcutaneously
implanted intraumbilical perinatal port system, as a treatment option for severe IUGR human
fetuses with brain sparing.
Background: Poor spinal anaesthesia block is common and is difficult to manage; so a
technique to minimize its incidence is advisable. Hypotension is the commonest problem with
spinal anesthesia. Multiple trials to prevent or combat hypotension using positional changes,
fluid therapy and the use of vasopressors were tried. However, the drug choice and mode of
administration as either bolus or infusion is still a matter of debate.
Objectives: To compare the outcome of spinal injection of hyperbaric bupivacaine and fentanyl
separately to standard injection of mixed fentanyl with hyperbaric bupivacaine.
Design: A randomized, controlled clinical trial.
Setting: Single medical center from 5/2013 to 10/2014.
Patients & Methods: 124 parturient scheduled for elective cesarean section (CS) were randomly
allocated into two groups, each 62 parturient: Group M received spinal anesthesia using 10 mg
bupivacaine 0.5% premixed with 25 µg fentanyl in the same syringe and Group S received 25 µg
fentanyl in one syringe and 10 mg bupivacaine 0.5% without barbotage in a second syringe.
Intravenous fluid co-load with 15 ml/kg warm lactated ringer solution was started as fast
drip during, and continued after spinal anesthesia.
Patients were monitored for hemodynamic parameters, time of sensory onset and height of
maximum sensory block, lower limb motor blockade was scored using modified Bromage scale and
the frequency of side effects.
This is an interventional drug trail to evaluate the effect of different intrathecal opioids
on post-operative pain experiences in women who have undergone caesarean section surgery.
The primary aim of the study is to evaluate the effects of two local cryotherapy (ice or cold
gas) applications on arthritic knees.
Evaluation criteria (before/after treatment):
– synovial power-Doppler semi-quantitative score
– pain VAS (mm)
– cytokine levels in synovial fluid
– leukocyte count in synovial fluid
The primary objective of this study is to assess the safety, tolerability and toxicity of
preoperative HBOT in patients undergoing a pancreaticoduodenal resection for premalignant and
malignant tumors of the common bile duct, periampullary and duodenum.
Dexmedetomidine, highly selective agonist for alpha-2 receptors, enhances the sensory and
motor block with prolonged postoperative analgesia without hemodynamic compromise.
OBJECTIVE: To evaluate effects of dexmedetomidine vs fentanyl with hyperbaric bupivacaine
spinal anesthesia for lower abdominal surgeries.
METHODS: double-blind, randomized, American Society Anesthesiologist classification (ASA) : I
– II, 18-65 years. F group (23 patients) received 25 mcg fentanyl, Group D (27 patients), 10
mcg dexmedetomidine with 12.5 mg hyperbaric bupivacaine . 0,02mgrs morphine / kg
intravenously if EVA≥4was administered in postoperative period. Hemodynamic variables and O2
saturation intraoperatively was recorded, EVA every 4 hours, side effects, sensory block,
motor, sedation and peripheral neurological manifestations of toxicity.
Diabetes and Periodontitis are both prevalent diseases affecting millions of Americans.
Periodontitis is prevalent among Diabetics. Furthermore, Periodontitis and associated
inflammation can increase insulin resistance in Diabetics and worsens the condition.
Hyperbaric Oxygen Therapy (HBOT) has the potential to improve periodontal treatment outcome
in poorly controlled diabetics. The study will compare periodontal treatment (SRP) outcome
between 2 main diabetic type 2 patient groups receiving medical care treatment: either
Conventional Wound Therapies (CWC) with or without adjunctive Hyperbaric Oxygen Therapy at
LLU Health.
24 poorly controlled diabetic mellitus (DM) type 2 subjects (HbA1c =>7%) with Periodontitis
will be assigned into the study arms HBO therapy and Non HBO therapy, based on their medical
needs.
For all subjects demographic data (age, gender, ethnicity, smoking history, alcohol use
history, BMI, current medication list) and oral health habits will be obtained. Blood samples
for HbA1c determinations, clinical periodontal measurements (plaque index, probing
measurements including pocket depth, attachment levels, gingival index and
bleeding-on-probing) and subgingival microbial samples will be obtained at baseline and end
of the study. Subgingival microbial samples will be collected from three randomly selected
sites and analyzed for detection of about 300 of the most prevalent oral bacterial species.
Differences in periodontal clinical outcomes and bacterial profiles will be identified
utilizing ANCOVA (Analysis of Covariance).
The purpose of this study is to examine the role of Hyperbaric Oxygen Therapy (HBOT) in
improving neurological function in patients who are 6 to 36 months post ischemic stroke.