Abstract: The efficacy and safety profile of hyperbaric oxygen therapy (HBOT) in patients with diabetic foot ulcer have been controversial in recent years. Our meta-analysis was undertaken to evaluate the efficacy and safety profile of HBOT in patients with diabetic...
Outcome and prognostic factors of patients treated in the intensive care unit for carbon monoxide poisoning.
Abstract: Carbon monoxide (CO), a colorless and odorless gas, is one of the common causes of poisoning-related deaths worldwide. CO poisoning can result in hypoxic brain damage and death, but intensive care can improve the likely outcome for critically ill patients....
The efficacy of hyperbaric oxygen therapy in the treatment of central retinal artery occlusion.
Abstract: Central retinal artery occlusion (CRAO) is an ophthalmological emergency. Various treatment modalities have been tried, but none have shown to alter natural history of the disease. Hyperoxia can restore retinal oxygenation, and favourable results were...
Italian COnsensus in Neuroradiological Anesthesia (ICONA).
Abstract: Anesthetic management of patients undergoing endovascular procedures for treating intracranial aneurysms or cerebrovascular malformations must consider a number of specific challenges, in addition to those associated with anesthesia for other specialties. In...
Perfluorocarbon emulsions radiosensitise brain tumors in carbogen breathing mice with orthotopic GL261 gliomas.
Abstract: Tumour hypoxia limits the effectiveness of radiation therapy. Delivering normobaric or hyperbaric oxygen therapy elevates pO2 in both tumour and normal brain tissue. However, pO2 levels return to baseline within 15 minutes of stopping therapy. To investigate...
Co-administration of tissue plasminogen activator and hyperbaric oxygen in ischemic stroke: a continued promise for neuroprotection.
Abstract: Intravenous recombinant tissue-type plasminogen activator (r-tPA, alteplase) remains the recommended therapy for acute ischemic stroke. However, several factors are limiting its practical use. It makes it urgent for us to search more efficient strategies...
Co-administration of tissue plasminogen activator and hyperbaric oxygen in ischemic stroke: a continued promise for neuroprotection.
Abstract: Intravenous recombinant tissue-type plasminogen activator (r-tPA, alteplase) remains the recommended therapy for acute ischemic stroke. However, several factors are limiting its practical use. It makes it urgent for us to search more efficient strategies...
Clinical Trial – Spinal Marginally Hyperbaric Ropivacaine for Cesarean Delivery
BACKGROUND: One previous study has confirmed that the marginally hyperbaric solutions of
bupivacaine can maintain good quality of anesthesia and get a more steadily hemodynamic
status than commonly hyperbaric solutions, some authors confirmed the plain ropivacaine for
cesarean section have a higher failure rate and commonly hyperbaric solutions of ropivacaine
have a higher incidence of side reaction. It is unclear what the efficacy of spinal
marginally hyperbaric ropivacaine for elective cesarean delivery.We hypothesized that the
marginally hyperbaric ropivacaine will get a similar efficacy to commonly hyperbaric
solutions but a more steadily hemodynamic status.
OBJECTIVE In this prospective, randomized, double-blinded study, Investigator will compare
the clinical efficacy and adverse effect of spinal anesthesia with commonly hyperbaric and
marginally hyperbaric ropivacaine for elective cesarean delivery.
Main outcome measures: The maximum cephalad sensory block level; the change of continuous
cerebral oxygen desaturation (ScO2) over time; the incidence of hypotension and nausea and
vomiting; the change of invasive arterial pressure; the consumption of ephedrine; the
incidence of shivering; the onset time to T8 dermatome; the quality of anesthesia (efficacy
of motor block and sensory block)
Clinical Trial – Comparison of Regional Anesthesia Techniques After Total Knee Arthroplasty
Comparison of continuous adductor canal block to continuous femoral nerve block in patients
after total knee arthroplasty.
All patients will be anesthetized with spinal anesthesia. Continuous infusion of ropivacaine
with a catheter implemented to the adductor canal or next to the femoral nerve.
The observed goals: pain intensity, the beginning and quality of rehabilitation.
Clinical Trial – Evaluation of Hyperbaric Oxygen Therapy on Wound Healing Following Management of Soft Tissue Sarcoma With Neo-Adjuvant Radiation and Surgical Resection
A prospective, randomized investigation with appropriate power would determine whether or not
postoperative hyperbaric oxygen therapy improves wound healing in patients with soft tissue
sarcoma undergoing surgical resection with neo-adjuvant radiation therapy.
