Periodontal Therapy in Severe Cases of Periodontitis: Preliminary Findings of Non-surgical Instrumentation With or Without Hyperbaric Oxygen Therapy (HBOT)
Description:
Materials and Methods: In 20 patients diagnosed with severe generalized chronic periodontitis
(pockets>7mm) with bleeding on probing, SRP was rendered in all pockets. Additionally, five
consecutive hyperbaric sessions were administered in 10 patients after random allocation
(SRP+HBOT). Clinical parameters were assessed at baseline up to 6 months: plaque index (PI),
bleeding on probing, probing depth, clinical attachment level and BANA test.
Results: SRP+HBOT resulted in greater probing reduction and attachment gain than SRP alone 3
months after treatment (p<0.001). The BANA test was negative after 1 week only for sites in
the SRP+HBOT group (p<0.05). However SRP+HBOT failed to show a significant difference from
SRP group after 3 months were all BANA sites became negative (p>0.05).
Conclusion: These preliminary data suggest that hyperbaric oxygen therapy had a short-term
beneficial effect on pocket reduction and bacterial elimination, and may be considered a
potential therapy option to improve the clinical outcomes of scaling in severe cases of
chronic periodontitis.
Condition:
Periodontal Disease
Treatment:
oxygen
Start Date:
March 2002
Sponsor:
Escola Bahiana de Medicina e Saude Publica
For More Information:
https://clinicaltrials.gov/show/NCT00955643