Radiation Induced Cystitis Treated With Hyperbaric Oxygen – A Randomized Controlled Trial
Description:
Radiotherapy is commonly used in the management of malignant diseases. Despite a continuous
improvement of the technique, with improved efficacy and tolerance, adverse effects are still
rather common. The urinary bladder and rectum are the major organs most commonly affected by
radiotherapy to the pelvis area.
One of the most significant causes of the symptoms of radio therapy is inflammation and
degeneration of blood vessels in the radiated tissue. Hyperbaric oxygen therapy involves
administration of oxygen at greater than normal atmospheric pressures. A well-documented
effect of HBOT is the stimulation of angiogenesis. HBOT is an established treatment for
degeneration of blood vessels in the jaw bone as a result of radiotherapy and several
publications have shown good efficacy also when soft tissue is affected.
If the method of treatment with HBOT means a reduction of the radiotherapy side effect it is
thus an obvious importance for the individual patient. There is also significant potential
savings for the healthcare and society.
Condition:
Cystitis, Radio Induced
Treatment:
Hyperbaric Oxygen
Start Date:
August 2012
Sponsor:
Göteborg University
For More Information:
https://clinicaltrials.gov/show/NCT01659723