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Recent HBOT News
VEGF and bFGF induction by nitric oxide is associated with hyperbaric oxygen-induced angiogenesis and muscle regeneration
Abstract: Hyperbaric oxygen (HBO) treatment promotes early recovery from muscle injury. Reactive oxygen species (ROS) upregulation is a key mechanism of HBO, which produces high O2 content in tissues through increased dissolution of oxygen at high pressure. Nitric...
Clinical Trial – Postoperative Urinary Retention in Orthopedic Patients
The objective of this study is to compare the incidence of postoperative urinary retention
related to spinal anesthesia with morphine and spinal anesthesia associated with peripheral
blockade in orthopedic procedures of lower limbs. Secondary objectives are assessing the
incidence of nausea and vomiting; postoperative pain and opioid consumption at 24 hours after
surgery with each of the techniques. A total of 52 patients submitted to a lower limb
orthopedic procedure were randomized to the intervention groups: spinal anesthesia with
morphine versus spinal anesthesia without opioid associated with peripheral nerve block.
After surgery, bladder ultrasound will be performed in post-anesthesia care unit to identify
urinary retention and patients will be followed for 24 hours to assess outcomes.
Clinical Trial – Autonomic Modulation After Spinal Anesthesia With Depth of Anesthesia and Vital Signs.
Spinal anaesthesia has the advantage that produced nerve block by the injection of local
anaesthetic into cerebrospinal fluid (CSF). However, the greatest challenge in spinal
anaesthesia is to control the spread of local anaesthetic through the CSF to provide a block
which is adequate for the proposed surgery without unnecessary extensive spread, and
increased risk of complications.