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Recent HBOT News
Clinical Trial – Effect of Hyperbaric Oxygen Therapy on Microcirculation
Previous studies shoes that hyperoxia alters microcirculation.The investigators hypothesize
that hyperbaric may restore microcirculation integrity. This hypothesis is supported by a
recent study in rabbits, but no data exists for humans.
The study will expose fifteen healthy volunteers to a succession of different fraction of
inspired oxygen and barometric pressure and assess microcirculatory and macrocirculatory
changes via sidestream dark field videomicroscopy, near-infrared spectroscopy, Laser Doppler,
transthoracic echocardiography and bio-impedancemetry at every step.
Clinical Trial – 3 Local Anesthetics for Spinal Anesthesia in Primary Total Hip Arthroplasty
Spinal anesthesia is commonly utilized for hip replacement surgery. Different medications
used for spinal anesthesia work for different lengths of time. This study will compare three
different spinal anesthesia medications in patients having hip replacement surgery to see if
patients are able to get out of bed and walk earlier after surgery with one medication versus
the others.
Clinical Trial – Comparision of Different Doses of Dexmedetomidine With Low Dose Bupivacaine in Selective Spinal Anesthesia.
The charactereistics of a spinal block varies with the dose of local anaesthetic and the
adjuvant used. Literature review did not show comparison of different doses of
dexmedetomidine with low-dose bupivacaine in saddle block. The rationale of this study is to
determine an optimum dose of dexmedetomidine which in combination with low dose bupivacaine
would provide satisfactory block with hemodynamic stability. This would be beneficial for
patients scheduled for turp, as these pts are mostly elderly with various comorbidities.


