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Recent HBOT News
Clinical Trial – Decompression Tables for Diving at Altitude
The aims of this proposal are to test current USN procedures for adjusting decompression
procedures during air diving at 8,000 and 10,000 ft altitude and to provide a decompression
algorithm for no-stop dives to 100 feet of sea water (fsw) at 10,000 and 12,000 ft altitude
using enriched O2 (PO2=1.3 ATM). Additionally, the experiments will determine whether a
period of hyperbaric hyperoxia, such as would be experienced during a dive at altitude,
reverses altitude acclimatization, resulting in a return of acute mountain sickness (AMS)
symptoms.
Hyperbaric oxygen therapy as an adjuvant to source control in necrotizing soft tissue infections.
Abstract: Necrotizing soft tissue infections (NSTI) are rare but potentially lethal disorders, and adequate management is time- and resource-demanding. This study aims to assess whether variations in the treatment modalities - surgery, hyperbaric oxygen (HBO₂) therapy...
The protection effect and mechanism of hyperbaric oxygen therapy in rat brain with traumatic injury.
To investigate the effect of hyperbaric oxygen therapy (HBOT) on traumatic brain injury (TBI) outcome. The modified Marmarou’s weight drop device was used to generate non-lethal moderate TBI rat model, and further developed in vitro astrocytes culturing system. Then, we analyzed the expression changes of interested genes and protein by quantitative PCR and western blot. Multiple HBO treatments significantly reduced the expression of apoptosis promoting genes, such as c-fos, c-jun, Bax and weakened the activation of Caspase-3 in model rats. On the contrary, HBOT alleviated the decrease of anti-apoptosis gene Bcl-2 and promoted the expression of neurotrophic factors (NTFs), such as NGF, BDNF, GDNF and NT-3 in vivo. As a consequent, the neuropathogenesis was remarkably relied with HBOT.


