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Recent HBOT News
Low-dose Spinal Block With Continuous Epidural Infusion for Renal Transplantation in a Patient With Alport Syndrome: A Case Report.
Abstract: We aim to describe management of a patient receiving renal transplantation for chronic renal failure due to Alport syndrome with low dose of intrathecal bupivacaine and continuous epidural infusion of local anesthetic. A 38-years-old man with chronic renal...
Low-dose Spinal Block With Continuous Epidural Infusion for Renal Transplantation in a Patient With Alport Syndrome: A Case Report.
Abstract: We aim to describe management of a patient receiving renal transplantation for chronic renal failure due to Alport syndrome with low dose of intrathecal bupivacaine and continuous epidural infusion of local anesthetic. A 38-years-old man with chronic renal...
Clinical Trial – Occult Carbon Monoxide Poisoning Detection by Pulsated Carboxymetry in an Emergency Department
In France, the carbon monoxide is one of the first causes of the accidental poisonings with
approximately 8000 cases a year, among which 500 deaths.
The severe forms are translated by neurological disorders even a coma or the death straight
away. The more insidious forms with a little carboxyhémoglobine level give rise to frustrate
clinical pictures, mimicking flu or intestinal syndromes. The syndrome post–intervallaire
corresponds to the appearance of remote neuropsychiatric disorders of the poisoning. Its
appearance and its gravity are not correlated in the gravity of the initial poisoning,
however the precocity of the treatment tends to decrease its frequency.
Carbon monoxide elimination is made under unchanged form in the expired air. In a spontaneous
way, the half-life in ambient air is of the order of 4 hours. In ventilation in isobaric pure
oxygen, the half-life is shortened at 80 minutes and in hyperbaric oxygen at 23 minutes.
This imposes a fast diagnosis for two reasons:
– For poisonings with low level, the more the investigators wait to measure the
carboxyhémoglobine (HBCO), the more they risk not to detect it.
– The oxygen therapy decreases the duration of the poisoning and thus the tissular
suffering.
Actually the risk is important to pass next to the diagnosis and to let leave a patient
without adapted care and without technical intervention to eliminate the source of the
poisoning.
Presently, to make the diagnosis, the investigators possess the analysis of the blood HbCO by
realization of gas of the venous blood, which are taken in emergencies, but very often a few
hours after the end of the exposure at the source of poisoning, what is translated by a
disappearance of the symptoms and an underestimate of the initial blood HbCO. Since 2005,
MASIMO laboratory commercialize a pulse carboxymètre, the RAD 57, which allows to estimate
the carboxyhémoglobinémie in a not invasive way.
Lot of studies showed the interest of its use in the early screening of carbon monoxide
poisonings, allowing a faster dosage of the blood HbCO, and thus an also faster adapted care.