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Recent HBOT News
Outcomes of Radiation Injuries Using Hyperbaric Oxygen Therapy: An Observational Cohort Study.
Abstract: The late effects of radiation therapy following the treatment of cancer are a well-known consequence. Evidence increasingly supports the use of hyperbaric oxygen (HBO) as an adjunctive treatment in a variety of radiation injuries. To present the findings of...
Hyperbaric Oxygen Preconditioning Attenuates Hemorrhagic Transformation Through Reactive Oxygen Species/Thioredoxin-Interacting Protein/Nod-Like Receptor Protein 3 Pathway in Hyperglycemic Middle Cerebral Artery Occlusion Rats.
Abstract: To clarify whether hyperbaric oxygen preconditioning can attenuate hyperglycemia-enhanced hemorrhagic transformation and to establish a role for Nod-like receptor protein 3 inflammasome in the pathophysiology of hemorrhagic transformation. Controlled...
Clinical Trial – The Effects of Height and Weight Adjusted Dose of Local Anesthetic.
At our centre a conventional dose of 12 mg of hyperbaric bupivacaine in combination with a
short acting opioid fentanyl (to increase block density) and a long acting opioid morphine
(to provide post-operative pain relief ) is used for spinal anesthesia for cesarean
section.However, larger doses of local anesthetic drug when used in caesarean section
commonly cause low blood pressure and requires drugs (vasopressors) to treat it. In our study
the investigators will standardize the doses of both opioids (fentanyl/morphine) and adjust
the dose of local anesthetic (bupivacaine) based on the patients height and weight .One of
the obvious challenges anesthesiologists face is providing adequate anesthesia to the patient
whilst minimizing harmful side effects. Our primary concern is the low blood pressure as an
effect of the spinal anesthetic as it is harmful to both mother and the baby. The
investigators propose that the extent of surgical anesthetic block, which is dependent on
height and weight in our adjusted dose group, will provide adequate anesthesia for surgery
and minimise maternal low blood pressure.