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Recent HBOT News
Clinical Trial – Cryotherapy and Doppler in Inflammatory Rheumatic Diseases
The primary aim of the study is to evaluate the effects of two local cryotherapy (ice or cold
gas) applications on arthritic knees.
Evaluation criteria (before/after treatment):
– synovial power-Doppler semi-quantitative score
– pain VAS (mm)
– cytokine levels in synovial fluid
– leukocyte count in synovial fluid
Clinical Trial – Pancreaticoduodenectomy With or Without Preoperative Hyperbaric Oxygen Therapy
The primary objective of this study is to assess the safety, tolerability and toxicity of
preoperative HBOT in patients undergoing a pancreaticoduodenal resection for premalignant and
malignant tumors of the common bile duct, periampullary and duodenum.
Clinical Trial – Subarachnoidal Anesthesia: Dexmedetomidine vs Fentanyl Plus Hyperbaric Bupivacaine for Lower Abdomen Surgery
Dexmedetomidine, highly selective agonist for alpha-2 receptors, enhances the sensory and
motor block with prolonged postoperative analgesia without hemodynamic compromise.
OBJECTIVE: To evaluate effects of dexmedetomidine vs fentanyl with hyperbaric bupivacaine
spinal anesthesia for lower abdominal surgeries.
METHODS: double-blind, randomized, American Society Anesthesiologist classification (ASA) : I
– II, 18-65 years. F group (23 patients) received 25 mcg fentanyl, Group D (27 patients), 10
mcg dexmedetomidine with 12.5 mg hyperbaric bupivacaine . 0,02mgrs morphine / kg
intravenously if EVA≥4was administered in postoperative period. Hemodynamic variables and O2
saturation intraoperatively was recorded, EVA every 4 hours, side effects, sensory block,
motor, sedation and peripheral neurological manifestations of toxicity.