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Recent HBOT News
Clinical Trial – Treatment of Cerebral Radiation Necrosis (CRN) With Nerve Growth Factor (NGF)
Cerebral radiation necrosis (CRN) is a well-documented late complication of radiation therapy
for cancers, and may have a devastating effect on the patient’s quality of life (QOL).
However,CRN was once regarded as a progressive and irreversible disease, no standard therapy
has been suggested for CRN. In our clinical practice, we have used nerve growth factor(NGF)
to treat CRN, and found that GM1 can successfully reverse CRN. A case report has been
published in Journal of Clinical Oncology (JCO) in 2011. So we carried out this prospective
study to test the efficacy of NGF for CRN.
Clinical Trial – Hemodynamic Effects of Low Dose Spinal Anesthesia for Cesarean Section
We propose to study the effects on hemodynamics (blood pressure, cardiac output, and central
venous pressure) of two doses of bupivacaine for spinal anesthesia during cesarean section: a
higher dose of 12 mg to a lower dose of 4.5 mg. We will examine recovery times, incidence of
hypotension, and compare pain control and maternal satisfaction during and after cesarean
section.
We hypothesize that low dose bupivacaine spinal anesthesia will provide equivalent anesthesia
for cesarean section compared to conventional dose bupivacaine, with less hypotension, faster
recovery time, and enhanced maternal satisfaction. Maternal satisfaction will be assessed by
self-reported pain scores, incidence of nausea and vomiting, shivering, and ability to
interact with baby in the OR.
Comparison of complications in free flap reconstruction for osteoradionecrosis in patients with or without hyperbaric oxygen therapy.
Abstract: Hyperbaric oxygen (HBO) therapy induces native tissue oxygenation. The hypothesis was patients with mandibular osteoradionecrosis (ORN) and a history of HBO therapy would have less free flap reconstruction complications than patients without HBO therapy. We...