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Recent HBOT News
Clinical Trial – Hyperbaric Treatment of Traumatic Brain Injury (TBI)
This study is designed to test the hypothesis that patients with Traumatic Brain Injury
(TBI)treated with Hyperbaric (HBO) will show improvement in function and an increased blood
flow as evidenced by single-photon emission computerized tomography (SPECT) scan. Improvement
is evidenced by increase in number of pixels on SPECT Scan and increased brain metabolism.
Improvement may also be identified via cognitive assessments administered by Jupiter Medical
Center Research Department.
Clinical Trial – Effects of Addition of Magnesium Sulfate in Spinal Anesthesia on Sensory-Motor Blocks and Postoperative Pain in Lumbar Disk Herniation Surgery
The purpose of this study is to Compare three methods of intrathecal bupivacaine;
bupivacaine-fentanyl; bupivacaine-fentanyl-magnesium sulfate on sensory-motor blocks and
postoperative pain in patients undergoing lumbar disk herniation surgery.
The protective effect of hyperbaric oxygen and Ginkgo biloba extract on Aβ25-35-induced oxidative stress and neuronal apoptosis in rats.
Alzheimer’s disease (AD) is characterized by accumulation and deposition of Aβ peptides in human brains. The present study aimed to determine the protective effect of HBO and EGB761 on Aβ25-35 peptides induced cognitive impairment and neuronal toxicity in rats. Characteristics of AD were induced in rats by the administration of Aβ25-35 in hippocampus. Rats were treated with HBO (2ATA 60min/day), EGB761 (20mg/kg/day), and the combination of HBO+EGB761 (20mg/kg/day+2ATA). The Morris water maze was used to detect the protective effects of HBO and EGB761 against cognitive impairment. The activities of SOD and GSH, the apoptosis-related genes and proteins and the apoptosis rate of hippocampus were detected. Compared to the model group, EGB761 and HBO treatments synergistically improved the escape latency. Furthermore, the activities of SOD and GSH in rat hippocampal tissue were found to have increased with a concomitant reduction in MDA levels, Bax expression, cytochrome c release, and the activity of caspase-9/3.