Clinical Trial – Hyperbaric Oxygen and Orthopedic Comprehensive Treatment for Traumatic Incomplete Spinal Cord Injury in the Plateau
To observe modified Barthel index, American Spinal Injury Association (ASIA) impairment scale
grading, sensory score and motor score in patients with incomplete SCI in the plateau using
0.2 MPa HBO combined with pedicle screw fixation and decompressive laminectomy so as to
investigate the effect of HBO therapy on incomplete SCI in the plateau.
Neuroprotective strategies for patients with acute myocardial infarction combined with hypoxic ischemic encephalopathy in the ICU.
Abstract: We investigated neuroprotective treatment strategies for patients with acute myocardial infarction (AMI) complicated with hypoxic ischemic encephalopathy (HIE) in the ICU. The 83 cases diagnosed with secondary AMI were, for the first time, divided into an...Effects of normobaric versus hyperbaric oxygen on cell injury induced by oxygen and glucose deprivation in acute brain slices.
Abstract: Normobaric oxygen (NBO) and hyperbaric oxygen (HBO) are emerging as a possible co-treatment of acute ischemic stroke. Both have been shown to reduce infarct volume, to improve neurologic outcome, to promote endogenous tissue plasminogen activator-induced...Clinical Trial – Pharmacokinetics of Levobupivacaine After Cesarean Section
Transversus abdominis plane (TAP) block provides effective analgesia and is now a standard of
care for analgesia after cesarean section. There is no information on levobupivacaine
pharmacokinetics post TAP after pregnancy.
Objective: Generate a pharmacokinetic levobupivacaine model and its effect on the
electrocardiogram (ECG).
Method: The investigators will study 12 healthy term pregnant patients, scheduled for
elective cesarean section under spinal anesthesia. A bilateral TAP block is performed with 20
ml 0.25% levobupivacaine with epinephrine 5 ug/ml. Sensory block will be assessed at 1-2-6
and 12 hours post puncture. 2 ml of venous blood will be obtained at 2-5-10-30-45-60-90 and
180 minutes. With a Holter machine we will study the effect of levobupivacaine plasma levels
and the QTc changes.
Expected results: 1) Plasma levobupivacaine levels; 2) Changes in QTc .