Veterans Special Report

Clinical Trial – Height Versus Height and Weight Based Spinal Bupivacaine on Maternal Haemodynamics for Elective Cesarean in Short Stature Patients

by | Sep 1, 2019 | Clinical Trials, HBOT Research, Maternal Hypotension After Spinal Anesthesia

Doses of intrathecal bupivacaine based on patients either height or height and weight has
shown to lower the risk of maternal hypotension with similar quality of anesthesia compared
to conventional doses.

In clinical practice there is a tendency of reducing the dose of bupivacaine as either low
fixed dose or using the doses based on either height and weight or height (0.06mg/cm) alone
in parturient with short stature. However, there is lack of evidence regarding the
appropriate dose required in this group of patients. Therefore, our aim is to compare the
height versus height and weight based intrathecal bupivacaine dose for elective caesarean on
maternal haemodynamics in short stature patients.

Clinical Trial – Plethysmographic Variability Index in Post Spinal Anesthesia Hypotension in Cesarean Section

by | Jul 3, 2019 | Clinical Trials, Complication of Anaesthesia During Labour and Delivery, HBOT Research

– Full term pregnant female patients presented for elective C.S for single viable fetus
will be included in this study.

– Before anesthesia, the patient will be attached to a monitor of: ECG , heart rate, non
invasive blood pressure, pulse taximeter applied on the index finger of the limb not
attached to the blood pressure cuff, pulse oximetry and plethysmographic variability
index (PVI) and perfusion index (PI) will be taken by (Massimo radical 7, Massimo corp.
USA). Measures will be recorded every 5 minutes preoperative.

– Patients with PVI <15 will be excluded from the study. - Patients with PVI > 15 are started on intravenous infusion of warm ringer lactate
solution via suitable pore intravenous cannula to reach target of PVI <15 or a total 1 liter of ringer lactate. - The patients in which the PVI is corrected by fluid to level below 15 will be Group (C) or corrected group. Patients in which intravenous fluid administration did not result any change in PVI or changed but still higher than 15 will be Group (NC) or non corrected group. After preoperative preparation patient is shifted to operating theater, with all monitors applied. She will receive spinal block at lumbar 3-4 space with hyperbaric bupivacaine 8 mg plus 25 mic fentanyl. After giving anesthesia and positioning for surgery with a left lateral tilt of 15 degrees,

Clinical Trial – Comparision of Different Doses of Dexmedetomidine With Low Dose Bupivacaine in Selective Spinal Anesthesia.

by | May 5, 2019 | Clinical Trials, Drug Effect, HBOT Research

The charactereistics of a spinal block varies with the dose of local anaesthetic and the
adjuvant used. Literature review did not show comparison of different doses of
dexmedetomidine with low-dose bupivacaine in saddle block. The rationale of this study is to
determine an optimum dose of dexmedetomidine which in combination with low dose bupivacaine
would provide satisfactory block with hemodynamic stability. This would be beneficial for
patients scheduled for turp, as these pts are mostly elderly with various comorbidities.