Clinical Trial – Caudal Block,Saddle Block, Anorectal Surgery

Anorectal surgery includes pilonidal sinus, hemorrhoidectomy, anal fissure, and anal fistula
operations. Various surgical and anesthetic techniques have been used to increase the level
of analgesia in perioperative period and decrease the length of stay in the hospital. In this
study, investigators investigate the effects of routinely applied anesthesia techniques
during anorectal surgery, caudal block and saddle block, on patients’ perioperative
hemodynamic values, sensory and motor block levels, and postoperative pain scores.

Clinical Trial – Effect of Different Types of Anesthesia on Perioperative Brain Natriuretic Peptide Levels in Parturient Cardiac Patient Undergoing Elective Cesarean Section

comparing the effect of general anesthesia versus spinal anesthesia on brain natruretic
peptide hormone levels preoperatively and postoperatively in parturient cardiac patient
undergoing cesarean section

Clinical Trial – SOFT Block Versus Spinal Anesthesia in Patientsusing Ilizarov External Fixator

Peripheral nerve block is an ideal choice for lower limb surgery because of the peripheral
site of the surgical procedure and the ability to block pain pathways at multiple levels. On
the contrary to other anesthetic techniques, as spinal or general anesthesia, properly
performed peripheral nerve blocks bypass adverse events as hemodynamic instability and
respiratory complications, properly treat post-operative pain leading to early hospital
discharge. Additional advantages of peripheral nerve blocks are that they can be used in
patients receiving anti-coagulants or lumbosacral disease in addition to avoidance of airway
instrumentation.

Recently, there has been a significant interest in regional anesthesia and peripheral nerve
blockade. This is facilitated by a significant advance of the research in this field and
availability of better equipment facilitating regional anesthesia.The aim of this study was
to assess the efficacy and safety of SOFT block (sciatic-obturator-femoral nerve block
technique) in comparison with spinal anesthesia in patients undergoing surgery for fixation
of open tibial fractures using Ilizarov external fixator.

Clinical Trial – Incidence of Postoperative Delirium in Cancer Patients After Laparoscopic Surgery in Trendelenburg Position

Postoperative delirium is an acute mental syndrome that is caused by diffuse cerebral
dysfunction resulting from the action of predisposing and precipitating factors acting
together. It is associated with an increase in mortality and postoperative morbidity and
prolongs the period of hospitalization of the patient Videolaparoscopic surgery has been
increasingly used as a therapeutic and diagnostic method. In order to have a good
visualization of the anatomical structures on which it will act, it is necessary to introduce
gas into the cavity, a mandatory component known as pneumoperitoneum. This technique gives
special characteristics for the conduction of anesthesia, since the positive intra-abdominal
pressure results in changes in the patient’s physiology. Some types of laparoscopic surgery
require the position of Trendelenburg for better visualization of the operative field. Among
the changes related to this position are the increase in cardiac output and intracranial
pressure.

In order to optimize the anesthetic procedure, anesthetic blocks have been increasingly used,
especially the spinal. The association of general anesthesia with spinal anesthesia, followed
by its contraindications is advantageous, because lower doses of anesthetic agents are
necessary for the maintenance of general anesthesia. This association results in an earlier
awakening, a reduction of nausea / vomiting, postoperative pain, length of hospital stay,
cost effectiveness and greater patient satisfaction. As a disadvantage, by associating
general anesthesia with spinal anesthesia, patients become susceptible to the adverse events
of spinal anesthesia. Among these, the most common are headache, hypotension, nausea and
vomiting, pruritus, urinary retention and tremor. Performing spinal anesthesia with opioids
alone, without the use of local anesthetic is also possible, with morphine being the most
used. The benefit of this variation of technique is analgesia for a period of 12 to 24 hours,
without the cardiovascular consequences resulting from the action of the local anesthetic.

JUSTIFICATION: There are no studies in the literature evaluating The objective of this study
is to analyze if the anesthetic techniques employed, general anesthesia or general anesthesia
associated with subarachnoid block, for videolaparoscopic oncologic surgeries, in
Trendelenburg position, differ in relation to the incidence of delirium in the postoperative
period.