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Recent HBOT News
Dying for a cure
CINCINNATI (WKRC) - Suicide among our members of the military and our veterans is now at its highest level ever, reaching an average of 24 deaths a day. Several scientific and medical studies link many of these suicides to physical brain damage suffered by combat...
Clinical Trial – The Effect of Hyperbaric OxygeN Therapy on brEast Cancer Patients With Late Radiation toxicitY – UMBRELLA HONEY Trial
The "Hyperbaric OxygeN therapy on brEast cancer patients with late radiation toxicity"
(HONEY) trial aims to evaluate the effectiveness of HBOT on late radiation toxicity in breast
cancer patients using the trial within cohorts (TwiCs) design.
Clinical Trial – Effect of Intravenous Magnesium on Post-spinal Fentanyl Induced Pruritus Incidence
Introduction: Adding opioids to local anesthetic solutions leads to enhanced anesthesia and
provide postoperative analgesia. Intrathecaly injected opioids have some side effects,
though. One of them is pruritus. Objective: We designed a randomized, double‐blinded,
placebo‐controlled study to evaluate prophylactic impact of continuous IV Magnesium 10mg/kg
over 30 minutes on intrathecal fentanyl‐induced pruritus start at the end of the operation.
Methods: ASA I‐II Patient’s candidate for orthopedic operations under spinal anesthesia
(10‐15mg hyperbaric bupivacaine and 25 µg fentanyl intrathecal) and will be divided randomly
into two groups:
Control group (Placebo group): bolus 100 ml nacl 0.9% at end of surgery Study group (Mg ++
group): (continuous IV Magnesium 10mg/kg in 100 ml Nacl0.9% over 30 minutes at end of
surgery).
Study outcome:
1. Hemodynamics: Systolic blood pressure, Mean arterial blood pressure, pulse rate, O2
saturation will be recorded in 5 min,10 min,30 min,60 min and every one hour till 6
hours after the operation.
2. Pruritus Patients were asked about existence (present=1,no=0), severity (mild=1,
modret=2, sever =3) and site of pruritus (Face(trigeminal) =1, neuroaxial(dermatome)=2),
1,2,4, and 6 hours after operation. Incidence of pruritus total group incidence %.
3. The incidence of PONV.



